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1.

Molecular mechanisms of brain water transport.

MacAulay, Nanna.

Nat Rev Neurosci; 22(6): 326-344, 2021 06.

Artículo en Inglés | MEDLINE | ID: mdl-33846637

2.

Toward New AQP4 Inhibitors: ORI-TRN-002.

Thormann, Michael; Traube, Nadine; Yehia, Nasser; Koestler, Roland; Galabova, Gergana; MacAulay, Nanna; Toft-Bertelsen, Trine L.

Int J Mol Sci; 25(2)2024 Jan 11.

Artículo en Inglés | MEDLINE | ID: mdl-38255997

3.

CSF hypersecretion versus impaired CSF absorption in posthemorrhagic hydrocephalus: a systematic review.

Ben-Shoshan, Shai David; Lolansen, Sara Diana; Mathiesen, Tiit Illimar; MacAulay, Nanna.

Acta Neurochir (Wien); 165(11): 3271-3287, 2023 11.

Artículo en Inglés | MEDLINE | ID: mdl-37642688

4.

Ventricular CSF proteomic profiles and predictors of surgical treatment outcome in chronic hydrocephalus.

Rostgaard, Nina; Olsen, Markus Harboe; Lolansen, Sara Diana; Nørager, Nicolas Hernandez; Plomgaard, Peter; MacAulay, Nanna; Juhler, Marianne.

Acta Neurochir (Wien); 165(12): 4059-4070, 2023 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-37857909

5.

Posthemorrhagic Hydrocephalus in Patients with Subarachnoid Hemorrhage Occurs Independently of CSF Osmolality.

Lolansen, Sara Diana; Rostgaard, Nina; Capion, Tenna; Norager, Nicolas H; Olsen, Markus Harboe; Juhler, Marianne; Mathiesen, Tiit Illimar; MacAulay, Nanna.

Int J Mol Sci; 24(14)2023 Jul 14.

Artículo en Inglés | MEDLINE | ID: mdl-37511234

6.

Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension.

Lakk, Monika; Hoffmann, Grace F; Gorusupudi, Aruna; Enyong, Eric; Lin, Amy; Bernstein, Paul S; Toft-Bertelsen, Trine; MacAulay, Nanna; Elliott, Michael H; Krizaj, David.

J Lipid Res; 62: 100145, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-34710431

7.

Clearance of activity-evoked K⁺ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor.

Toft-Bertelsen, Trine Lisberg; Larsen, Brian Roland; Christensen, Sofie Kjellerup; Khandelia, Himanshu; Waagepetersen, Helle S; MacAulay, Nanna.

Glia; 69(1): 28-41, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-32506554

8.

Reply to 'Aquaporin 4 and glymphatic flow have central roles in brain fluid homeostasis'.

MacAulay, Nanna.

Nat Rev Neurosci; 22(10): 651-652, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34408335

9.

Pannexin 1 activation and inhibition is permeant-selective.

Nielsen, Brian Skriver; Toft-Bertelsen, Trine Lisberg; Lolansen, Sara Diana; Anderson, Connor L; Nielsen, Morten Schak; Thompson, Roger J; MacAulay, Nanna.

J Physiol; 598(2): 361-379, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31698505

10.

Structural determinants underlying permeant discrimination of the Cx43 hemichannel.

Nielsen, Brian Skriver; Zonta, Francesco; Farkas, Thomas; Litman, Thomas; Nielsen, Morten Schak; MacAulay, Nanna.

J Biol Chem; 294(45): 16789-16803, 2019 11 08.

Artículo en Inglés | MEDLINE | ID: mdl-31554662

11.

Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type-specific and mediated by an N-terminal volume-sensing domain.

Toft-Bertelsen, Trine L; Yarishkin, Oleg; Redmon, Sarah; Phuong, Tam T T; Krizaj, David; MacAulay, Nanna.

J Biol Chem; 294(48): 18421-18434, 2019 11 29.

Artículo en Inglés | MEDLINE | ID: mdl-31619514

12.

Molecular mechanisms of K⁺ clearance and extracellular space shrinkage-Glia cells as the stars.

MacAulay, Nanna.

Glia; 68(11): 2192-2211, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-32181522

13.

Developmental maturation of activity-induced K⁺ and pH transients and the associated extracellular space dynamics in the rat hippocampus.

Larsen, Brian Roland; Stoica, Anca; MacAulay, Nanna.

J Physiol; 597(2): 583-597, 2019 01.

Artículo en Inglés | MEDLINE | ID: mdl-30357826

14.

Permeant-specific gating of connexin 30 hemichannels.

Nielsen, Brian Skriver; Alstrom, Jette Skov; Nicholson, Bruce J; Nielsen, Morten Schak; MacAulay, Nanna.

J Biol Chem; 292(49): 19999-20009, 2017 12 08.

Artículo en Inglés | MEDLINE | ID: mdl-28982982

15.

When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor.

Toft-Bertelsen, Trine L; Krizaj, David; MacAulay, Nanna.

J Physiol; 595(11): 3287-3302, 2017 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-28295351

16.

Aquaporin 4 as a NH3 Channel.

Assentoft, Mette; Kaptan, Shreyas; Schneider, Hans-Peter; Deitmer, Joachim W; de Groot, Bert L; MacAulay, Nanna.

J Biol Chem; 291(36): 19184-95, 2016 09 02.

Artículo en Inglés | MEDLINE | ID: mdl-27435677

17.

Regulation of the Water Channel Aquaporin-2 via 14-3-3Î¸ and -Î¶.

Moeller, Hanne B; Slengerik-Hansen, Joachim; Aroankins, Takwa; Assentoft, Mette; MacAulay, Nanna; Moestrup, Soeren K; Bhalla, Vivek; Fenton, Robert A.

J Biol Chem; 291(5): 2469-84, 2016 Jan 29.

Artículo en Inglés | MEDLINE | ID: mdl-26645691

18.

Activity-dependent astrocyte swelling is mediated by pH-regulating mechanisms.

Larsen, Brian Roland; MacAulay, Nanna.

Glia; 65(10): 1668-1681, 2017 10.

Artículo en Inglés | MEDLINE | ID: mdl-28744903

19.

The α2ß2 isoform combination dominates the astrocytic Na⁺ /K⁺ -ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation.

Stoica, Anca; Larsen, Brian Roland; Assentoft, Mette; Holm, Rikke; Holt, Leanne Melissa; Vilhardt, Frederik; Vilsen, Bente; Lykke-Hartmann, Karin; Olsen, Michelle Lynne; MacAulay, Nanna.

Glia; 65(11): 1777-1793, 2017 11.

Artículo en Inglés | MEDLINE | ID: mdl-28787093

20.

Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells.

Rosenbaek, Lena L; Rizzo, Federica; MacAulay, Nanna; Staub, Olivier; Fenton, Robert A.

Am J Physiol Renal Physiol; 313(2): F495-F504, 2017 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-28515174

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Molecular mechanisms of brain water transport.

Toward New AQP4 Inhibitors: ORI-TRN-002.

CSF hypersecretion versus impaired CSF absorption in posthemorrhagic hydrocephalus: a systematic review.

Ventricular CSF proteomic profiles and predictors of surgical treatment outcome in chronic hydrocephalus.

Posthemorrhagic Hydrocephalus in Patients with Subarachnoid Hemorrhage Occurs Independently of CSF Osmolality.

Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension.

Clearance of activity-evoked K⁺ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor.

Reply to 'Aquaporin 4 and glymphatic flow have central roles in brain fluid homeostasis'.

Pannexin 1 activation and inhibition is permeant-selective.

Structural determinants underlying permeant discrimination of the Cx43 hemichannel.

Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type-specific and mediated by an N-terminal volume-sensing domain.

Molecular mechanisms of K⁺ clearance and extracellular space shrinkage-Glia cells as the stars.

Developmental maturation of activity-induced K⁺ and pH transients and the associated extracellular space dynamics in the rat hippocampus.

Permeant-specific gating of connexin 30 hemichannels.

When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor.

Aquaporin 4 as a NH3 Channel.

Regulation of the Water Channel Aquaporin-2 via 14-3-3Î¸ and -Î¶.

Activity-dependent astrocyte swelling is mediated by pH-regulating mechanisms.

The α2ß2 isoform combination dominates the astrocytic Na⁺ /K⁺ -ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation.

Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells.